when I built my motor with the cummins pump I did some research into the RPM limit of the 12mm pump head, and found that the 4000 limit is for six cylinder motors.
four cylinder motors pump fewer times per revolution, so the safe rpm limit is higher(more like 6000)
I ran the 12mm pump as high as 5000 rpm with no issues.
as for tuning, with the larger pump head the injection event is shorter, making injecting large amounts of fuel require less advance.
other than that, they tune the same, just lots more clatter.
-Owen